Whether airway mucosal acidification drives early progressive lung disease is controversial ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018

Early life lower respiratory tract illness impairs lung function at 1 year, independent of baseline lung function ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

There is growing evidence that lung function in early-life predicts later lung function. Adverse events over the lifespan might influence an individual’s lung function trajectory, resulting in poor respiratory health. The aim of this study is to identify early-life risk factors and their impact on lung function trajectories to prevent long-term lung impairments. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• March 2022

Analysis of worldwide research shows that despite advances in neonatal care, preterm babies have lower lung function throughout their life. ...

• Wal-yan Respiratory Research Centre
• News & events
• 2022
• August

Interleukin-1 is associated with inflammation and structural lung disease in young children with cystic fibrosis Discover. Prevent. Cure. Early ...

• Wal-yan Respiratory Research Centre
• Projects
• AREST CF (Cystic Fibrosis)
• Publications

Lung function testing and lung imaging are commonly used techniques to monitor respiratory diseases, such as cystic fibrosis (CF). The nitrogen (N2) multiple-breath washout technique (MBW) has been shown to detect ventilation inhomogeneity in CF, but the underlying pathophysiological processes that are altered are often unclear. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• Jun 2023

Arsenic is the only environmental toxin that has been linked to both malignant and nonmalignant respiratory disease following ingestion, rather than inhalation, making arsenic a unique toxicant to the respiratory system. Chronic exposure to arsenic has been associated with the development of respiratory symptoms, impaired lung function, and chronic lung disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023

Children’s interstitial and diffuse lung disease (chILD) is a complex heterogeneous group of lung disorders. Gene panel approaches have a reported diagnostic yield of ~ 12%. No data currently exist using trio exome sequencing as the standard diagnostic modality. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

Kathryn Ramsey KR BSc (Hons), PhD Co-Head, Children's Lung Health kathryn.ramsey@telethonkids.org.au Co-Head, Children's Lung Health Associate ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

In this cohort, as compared with the AREST CF cohort, the authors highlight the limited correlation between infection and inflammation with lung function and structural impairment, and that this was mainly explained by the mild changes identified in lung function and on chest CT scan. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020